美国贝勒医学院张笑天博士学术报告通知

发布者:喻庆勇发布时间:2016-11-28浏览次数:966

  应我校生命学院蒋庆华教授邀请,美国贝勒医学院张笑天博士将于2016113日来我校进行学术交流并做学术报告,欢迎感兴趣的师生参加。

  题目:Co-operationof DNA Methylation Regulators inLeukemogenesis

  时间:2016113(周四)上午10:00

  地点:科学园2E411报告厅

  报告人简介:

  张笑天博士2010年本科毕业于复旦大学,2016年博士毕业于美国贝勒医学院。随后,在美国贝勒医学院MargaretGoodell实验室从事博士后研究。将从20171月起,赴任美国VANANDEL Institute独立fellow并建立独立实验室。张笑天博士的研究兴趣包括DNA甲基化调控因子及染色质高级结构在白血病发生中的作用。已在NatureGeneticsNaturePNASCancerCellCellStem Cell等国际知名刊物发表10余篇科研论文,代表性论文有:

1.Zhang  X,  Su J, Jeong M, Ko M, Huang Y, Park H, Rao A, Li W, Goodell MA. Dnmt3a and Tet2  interact to repress lineage specific transcriptional factors in hematopoietic  stem cells. Nature  Genetics, 2016 Sep;48(9):1014-23.2.
2.Karlstaedt  A, Zhang X, Vasquez H,  Wang J, Goodell MA, Taegtmeyer H. D-2 hydroxyglutaric acid impairs oxidative  decarboxylation by α-ketoglutarate dehydrogenase in rodent heart. Proc Natl AcadSci U S A, 2016 Aug  31. pii: 201601650.

3.Yang  L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau  D, Zhang X, Zhou T, Zhou  M, Rebel VI, Challen GA, Göttgens B, Lee JS, Rau R, Li W, Goodell MA.Cancer Cell. 2016 Jun  13;29(6):922-34.

4.Luo  M, Jeong M, Sun D, Park HJ, Rodriguez BA, Xia Z, Yang L, Zhang X, Sheng K, Darlington GJ,  Li W, Goodell MA. Long non-coding RNAs control hematopoietic stem cell function.  Cell Stem Cell. 2015 Apr  2;16(4):426-38.

5.Jeong  M, Sun D, Luo M, Huang Y, Challen GA, Rodriguez B, Zhang X, Chavez L, Wang H, Hannah  R, Kim SB, Yang L, Ko M, Chen R, Göttgens B, Lee JS, Gunaratne P, Godley LA,  Darlington GJ, Rao A, Li W, Goodell MA. Large conserved domains of low DNA  methylation maintained by Dnmt3a. Nature Genetics. 2014 Jan;  46(1):17-23.

6.Chen  X, Cui D, Papusha A, Zhang  X, Chu C-D, Tang J, Chen K, Pan X, Ira G (2012). The Fun30 nucleosome  remodeler promotes resection of DNA double-strand break ends. Nature, 2012 Sep  27;489(7417):576-80.

7.Wang  H, Wu W, Wang HW, Wang S, Chen Y, Zhang X, Yang J, Zhao S, Ding HF,  Lu D. Analysis of specialized DNA polymerases expression in human gliomas:  association with prognostic significance. Neuro Oncol. 2010  Jul;12(7):679-86